Nothing, everything is normal. in fact, the emails have been sent, the only problem is that no response to the user that emails have been sent.
I think the problem is the long time that send email with many recipients and big attachment and the script is stopped before all emails have been sent.
I do not know if he's related to the values "max_execution_time = 30" and "max_input_time = 60" (from php.ini). I don't know the optimal settings for roundcube