Unable to perform operation. Permission denied

[1cookie]

hi
The message is pretty clear. It looks like a permissions error, but which directory pertaining to Roundcube do I enhance permissions to? I'm on a Unix box (server) with a dovecot, roundcube and sendmail combo. I can access roundcube from a browser logging in with user 'mail'. When in RC, I try and click on inbox, receiving the message above. If I go deeper (the command line) I can send/receive emails to and from mutt successfully for user mail.  Prior to all this, I made a change to my

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dovecot.conf file, like so:

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mail_location = mbox:~/mail:INBOX=/var/mail/%u:INDEX=/var/indexes/%u

Can you offer some advice?